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Binucleated cells are cells that contain two nuclei. This type of cell is most commonly found in cancer cells and may arise from a variety of causes. Binucleation can be easily visualized through staining and microscopy. In general, binucleation has negative effects on cell viability and subsequent mitosis. ==Causes== * Cleavage furrow regression: Cells divide and almost complete division but then the cleavage furrow begins to regress and the cells merge. This is thought to be caused by nondisjunction in chromosomes but the mechanism by which it occurs is not well understood. * Failed cytokinesis: The cell can fail to form a cleavage furrow, leading to both nuclei remaining in one cell.〔 * Multipolar spindles: Cells contain three or more centrioles, resulting in multiple poles. This leads to the cells pulling chromosomes in many directions that end in multiple nuclei found in one cell.〔 * Merging of newly formed cells: Two cells that have just finished cytokinesis merge into one another. This process is not entirely understood.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「binucleated cells」の詳細全文を読む スポンサード リンク
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